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The net effect of general anesthetic-induced immunosuppression on the host-defense mechanisms against infection, cancer, and other disease processes is ill-defined. Most studies to date have provided conflicting results. The variety of methods employed and the fact that the effects of general anesthetic agents on cellular and humoral immune mechanisms are not clearly defined prevent definitive answers to questions about immunomodulation from being reached. In the present review, the literature on anesthetic-induced changes in the immune system is summarized. It is concluded that in most instances there is no appreciable general immunosuppressive effect of anesthetic agents on the immune response. However, certain anesthetics appear to have the ability to directly modulate subpopulations of lymphocytes. In view of the variety of clinical situations in which general anesthetic agents are used, the possible pathogenetic mechanisms of anesthetic-induced immunosuppression are discussed.Q:
Is there a way to expose or reload the RStudio kernel?
I have a series of expressions that I'd like to use in a group of kernel cells to construct and then use in a larger piece of code. I'm using functions from the tm package, and thus I had to add an option to findCells() to download all the data I need for tm to run. Unfortunately, when the kernel is closed for reasons, the data is not loaded.
My question is, is there any way to temporarily reload the kernel or otherwise get the functions from my tm packages to run again? I'm thinking something along the lines of on.exit() or on.init(). The cell environment will be closed, so 0b46394aab